Vol.31 Learn the knack of taking Cialis by looking at the graph

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【Learn the knack of taking Cialis by looking at the graph】

 

This time, we introduce you to the knack of taking Cialis (generic name : Tadalafil). Cialis is a long acting-type of ED curative which is very different from the other ED curatives (Viagra and Levitra) in the change of the blood concentration after taking it. Generally, because the strength of the effectiveness of the medicine is proportional to the blood concentration, we can say that the change of the blood concentration can be related to the change of the effectiveness. The graph below shows the change of the blood concentration after taking Cialis.

Cialis blood concentration graph (5-mg / 10-mg / 20-mg)

Cialis blood concentration graph (5-mg / 10-mg / 20-mg)

Each plot is 0, 0.5, 1, 1.5, 2, 3, 4, 8, 16, 24, 48 hours after administration)

You can see by looking at the graph that the peak of the blood concentration from the Cialis is shown near 3 hours after taking it. The timing and the peak will vary depending on the speed of digestion absorption, physical size (circulating-plasma-volume), combined medicine, and whether it is being taken every day, but the strongest effect should be expected in 1.5 hours to 8 hours roughly. Compared with Levitra which is characterized by the fast-acting property, the time that takes before getting to the peak is about four times more. However the peak period of time continues four times longer, so we can see the Cilias’s characteristic where once it starts working it offers great flexibility in timing.
As for the recommended way of taking it which takes advantage of this characteristic, taking it about 30 minutes before meal, and next enjoy the food and drinks for about 2-3 hours with your partner, and then having a sexual intercourse with your partner would be the best way. In this way, Cialis can be absorbed while eating and also you can spend the time with your partner before the effectiveness reaches to the peak. But as a weak point, in the case that you get dumped by your partner, you end up wasting all the effectiveness…..
At last, you can still expect a sufficient effectiveness in general when the blood concentration is still in the range of 50-60μg/L although the effectiveness will be less compared with the peak. So even if you are dumped by your partner tonight, you can possibly have another chance tomorrow.

 

【Supervisor of this article】

Ken Takemori, MD. An anesthesiologist and Director of Shibuya 3rd Block Clinic.

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