Vol.33 Learn the knack when taking Levitra by looking at the graph

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【Learn the knack when taking Levitra by looking at the graph】


Levitra (generic name:Vardenafil) is very popular medicine as the latest fast acting-type ED curative. In the previous column we explained about the characteristic of how Cilias can be effective and the knack of the way of taking it while referring to the blood concentration graph. This time, let us see the blood concentration graph for Levitra. Generally, because the strength and the effectiveness of the medicine are proportional to the blood concentration, we can say that the change in the blood concentration can be related to the change of the effectiveness.

Levitra blood concentration graph (10-mg / 20-mg)

Levitra blood concentration graph (10-mg / 20-mg)

(Each plot is 0, 0.25, 0.5, 0.75, 1, 1.25, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 10, 12, 16 hours of after administration)

Drawing figures based on the clinical pharmacodynamics: 34(1)197S(2003).
First, we can see the immediate effect of Levitra which promptly reaches the peak of the effect within 45 minutes after taking it. The blood concentration is high during the period from 20 minutes up to 3 hours after taking it, which shows a strong effect. As for the effect before and after the peak it is staying at about 1/4 compared with the one at the peak. We can see “the immediate but short time effect” of Levitra’s characteristic from the steep curve in the graph. However, you can still expect sufficient effect with about 1μg/L, so up to 5-6 hours after taking it in the case of a 10-mg tablet and 8-10 hours in the case of a 20-mg tablet, you can expect to have the effect, although it’ll be less effective compared with one at the peak.
Considering this characteristic, what we can recommend is taking it just before (about 30 minutes) the sexual activity in any event. This is the way of maximizing the characteristic of Levitra, but it is likely taking it after meals so then you need to be careful with the contents of the meal. When it’s mixed with fatty food, the absorption becomes bad as this is Levitra’s weak point. Therefore, trying not having fatty food is most important. If by any chance, you have any fatty food, you could take a stronger one (20 mg tablet), in anticipation that the effect will be decreased by half.


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